Interactor 1: LOX12 (P18054)
Polyunsaturated fatty acid lipoxygenase ALOX12 (EC 1.13.11.-) (Arachidonate (12S)-lipoxygenase) (12S-LOX) (12S-lipoxygenase) (EC 1.13.11.31) (Arachidonate (15S)-lipoxygenase) (EC 1.13.11.33) (Linoleate (13S)-lipoxygenase) (Lipoxin synthase 12-LO) (EC 3.3.2.-) (Platelet-type lipoxygenase 12)
Gene: ALOX12

Interactor 2: LOX12 (P18054)
Polyunsaturated fatty acid lipoxygenase ALOX12 (EC 1.13.11.-) (Arachidonate (12S)-lipoxygenase) (12S-LOX) (12S-lipoxygenase) (EC 1.13.11.31) (Arachidonate (15S)-lipoxygenase) (EC 1.13.11.33) (Linoleate (13S)-lipoxygenase) (Lipoxin synthase 12-LO) (EC 3.3.2.-) (Platelet-type lipoxygenase 12)
Gene: ALOX12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.710

The method score is based on:

Property Details
Experiments 18155727
Identification Methods x-ray crystallography, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Lipoxygenase~Lipoxygenase, Lipoxygenase~PLAT, PLAT~PLAT
Common GO terms GO:0004052 - arachidonate 12(S)-lipoxygenase activity
GO:0005506 - iron ion binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006629 - lipid metabolic process
and 20 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 663
Hs

1 663
+ Hs
+ Zm
+ Zm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024