Interactor 1: ERCC2 (P18074)
General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein)
Gene: ERCC2

Interactor 2: XPA (P23025)
DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein)
Gene: XPA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18597777
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C_2~XPA_C
Common GO terms GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006289 - nucleotide-excision repair
GO:0009650 - UV protection
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 760
Hs

1 273
+ Sc

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Last updated: 15 Jul 2024