Interactor 1: ERCC2 (P18074)
General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein)
Gene: ERCC2

Interactor 2: ERCC5 (P28715)
DNA excision repair protein ERCC-5 (EC 3.1.-.-) (DNA repair protein complementing XP-G cells) (XPG) (Xeroderma pigmentosum group G-complementing protein)
Gene: ERCC5

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.639

The method score is based on:

Property Details
Experiments 32245994, 8652557
Identification Methods pull down, affinity chromatography technology, coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006283 - transcription-coupled nucleotide-excision repair
GO:0006289 - nucleotide-excision repair
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 760
Hs

1 1186
+ Sc
+ Sc
+ Hs

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Last updated: 15 Jul 2024