Interactor 1: ERCC2 (P18074)
General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein)
Gene: ERCC2

Interactor 2: MMS19 (Q96T76)
MMS19 nucleotide excision repair protein homolog (hMMS19) (MET18 homolog) (MMS19-like protein)
Gene: MMS19

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.734

The method score is based on:

Property Details
Experiments 28178521, 23585563, 11071939, 22678362, 22678361, unassigned1353
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005675 - transcription factor TFIIH holo complex
GO:0005737 - cytoplasm
GO:0005819 - spindle
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 760
Hs

1 1030
+ Hs
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024