HitPredict

Interactor 1: BMP7 (P18075)
Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa)
Gene: BMP7

Interactor 2: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	25416956, 32296183, 31515488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0007411 - axon guidance GO:0008201 - heparin binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 236
+	Hs
		66522 A8K571_HUMAN (1-431): 0: 536: 100.00		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		484563 BMP7_HUMAN (1-431): 0: 536: 100.00		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Hs
		351256 TGFB1_HUMAN (30-430): 3.2e-82: 259: 20.10		TENX_HUMAN (1-184): 1.31e-24: 103: 24.06
+	Hs
		155775 GDF8_HUMAN (47-430): 4.23e-86: 269: 21.56		JAG2_HUMAN (8-209): 1.76e-16: 80.1: 31.86
+	Hs
		885339 INHBE_HUMAN (243-430): 6.39e-19: 89.4: 31.94		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84