HitPredict

Interactor 1: ITB5 (P18084)
Integrin beta-5
Gene: ITGB5

Interactor 2: MFGM (Q08431)
Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin]
Gene: MFGE8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 799 Hs			1 387
+	Hs
		216377 ITB5_HUMAN (1-799): 0: 786: 100.00		EDIL3_HUMAN (16-387): 5.16e-165: 472: 47.73
+	Hs
		574575 ITB5_HUMAN (1-799): 0: 786: 100.00		CNTP3_HUMAN (263-387): 2.49e-37: 145: 37.01
+	Dm
		247192 TENM_DROME (597-733): 3.98e-15: 82.4: 16.79		Q9VU94_DROME (78-387): 3.42e-80: 270: 24.48
+	Mm
		82715 B9EJ72_MOUSE (557-741): 1.95e-27: 122: 17.80		CNTP2_MOUSE (263-387): 8.92e-40: 152: 36.22
+	Mm
		1112697 TEN4_MOUSE (557-727): 7.92e-24: 110: 18.08		CNTP2_MOUSE (263-387): 8.92e-40: 152: 36.22
+	Hs
		132256 DLL1_HUMAN (483-718): 1.51e-24: 111: 18.01		DDR1_HUMAN (225-387): 2.83e-35: 139: 26.79
+	Mm
		1321670 TEN1_MOUSE (593-740): 3.28e-15: 82.4: 11.35		CNTP2_MOUSE (263-387): 8.92e-40: 152: 36.22