HitPredict

Interactor 1: ITB5 (P18084)
Integrin beta-5
Gene: ITGB5

Interactor 2: ADA21 (Q9UKJ8)
Disintegrin and metalloproteinase domain-containing protein 21 (ADAM 21) (EC 3.4.24.-)
Gene: ADAM21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0046872 - metal ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 799 Hs			1 722
+	Hs
		574536 ITB5_HUMAN (1-799): 0: 786: 100.00		ADAM9_HUMAN (26-722): 0: 570: 35.25
+	Hs
		574584 ITB5_HUMAN (1-799): 0: 786: 100.00		ADA30_HUMAN (32-721): 9.83e-154: 467: 39.66
+	Hs
		574574 ITB5_HUMAN (1-799): 0: 786: 100.00		ADA33_HUMAN (78-683): 1.48e-125: 394: 30.02
+	Hs
		396587 ITB3_HUMAN (4-788): 0: 716: 53.87		ADA15_HUMAN (58-665): 1.72e-130: 409: 29.46
+	Hs
		556492 ITB4_HUMAN (4-717): 0: 607: 32.65		ADA30_HUMAN (32-721): 9.83e-154: 467: 39.66
+	Rn
		824608 ITB1_RAT (8-789): 0: 723: 41.68		ADA17_RAT (10-517): 5.54e-59: 215: 20.20
+	Hs
		403857 ITB1_HUMAN (8-789): 0: 716: 41.68		ADA17_HUMAN (51-529): 6.14e-59: 215: 20.50
+	Hs
		152225 ITB1_HUMAN (8-789): 0: 716: 41.68		ADA10_HUMAN (338-514): 6.58e-11: 67.8: 29.65
+	Hs
		152344 TEN3_HUMAN (559-740): 5.88e-25: 114: 15.96		ADA10_HUMAN (338-514): 6.58e-11: 67.8: 29.65
+	Dm
		1368955 TENA_DROME (559-735): 1.6e-23: 109: 21.08		Q9VJW9_DROME (338-508): 5.71e-12: 71.6: 30.39
+	Dm
		246960 TENM_DROME (597-733): 3.98e-15: 82.4: 16.79		Q9VAI2_DROME (338-507): 5.15e-18: 91.3: 34.36
+	Dm
		247067 TENM_DROME (597-733): 3.98e-15: 82.4: 16.79		Q9VJW9_DROME (338-508): 5.71e-12: 71.6: 30.39