HitPredict

Interactor 1: ARF4 (P18085)
ADP-ribosylation factor 4
Gene: ARF4

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016477 - cell migration GO:0043066 - negative regulation of apoptotic process GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 180 Hs			1 894
+	Hs
		674380 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		UFO_HUMAN (1-894): 0: 780: 100.00
+	Hs
		912916 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		EPHA7_HUMAN (2-837): 0: 621: 19.50
+	Hs
		665572 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		EPHB2_HUMAN (2-837): 0: 605: 19.58
+	Hs
		665196 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		EPHA2_HUMAN (3-837): 0: 604: 19.66
+	Hs
		665207 ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00		EPHA2_HUMAN (3-837): 0: 604: 19.66
+	Hs
		872520 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		EPHB4_HUMAN (2-836): 1.08e-180: 549: 20.49
+	Hs
		574601 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		EPHA8_HUMAN (2-824): 0: 590: 19.20
+	Hs
		574656 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		TIE2_HUMAN (16-809): 3.58e-164: 510: 23.90
+	Hs
		411349 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		INSR_HUMAN (272-851): 1.65e-136: 443: 27.97
+	Rn
		102471 G3V6H0_RAT (5-180): 7.12e-67: 204: 22.65		INSR_RAT (276-851): 1.26e-134: 437: 27.83
+	Hs
		441426 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		574657 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		RON_HUMAN (518-810): 1.36e-56: 214: 40.47
+	Hs
		601491 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46
+	Hs
		574596 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29
+	Hs
		987290 RAB1B_HUMAN (5-180): 1.74e-67: 206: 22.65		TYRO3_HUMAN (8-328): 1.16e-14: 80.5: 16.42
+	Hs
		507840 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435530 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07
+	Hs
		507936 RAB1A_HUMAN (3-180): 6.71e-68: 207: 22.40		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69