HitPredict

Interactor 1: ARF4 (P18085)
ADP-ribosylation factor 4
Gene: ARF4

Interactor 2: COPG1 (Q9Y678)
Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)
Gene: COPG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~Arf
Common GO terms	GO:0000139 - Golgi membrane GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 180 Hs			1 874
+	Hs
		913217 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		913157 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		950752 ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		950585 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		950736 ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		574769 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		897411 ARF3_HUMAN (1-180): 2.97e-67: 204: 78.89		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Dm
		778370 ARF4_DROME (1-180): 9.61e-69: 208: 84.44		COPG_DROME (11-874): 0: 719: 60.28
+	Dm
		897447 ARF1_DROME (1-179): 6.66e-67: 203: 82.12		COPG_DROME (11-874): 0: 719: 60.28
+	Hs
		912875 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Hs
		950481 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Hs
		912839 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP2B1_HUMAN (14-871): 0: 591: 12.40
+	Hs
		321520 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP2A1_HUMAN (24-874): 0: 582: 14.63
+	Dm
		778364 ARF4_DROME (1-180): 9.61e-69: 208: 84.44		Q24253_DROME (14-872): 0: 629: 13.50
+	Dm
		897433 ARF1_DROME (1-179): 6.66e-67: 203: 82.12		Q24253_DROME (14-872): 0: 629: 13.50
+	Hs
		212615 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		AP1G1_HUMAN (17-741): 2.63e-170: 516: 15.52
+	Hs
		212618 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		AP1G1_HUMAN (17-741): 2.63e-170: 516: 15.52
+	Sc
		503061 ARF1_YEAST (1-179): 1.79e-65: 200: 72.63		COPG_YEAST (7-873): 7.79e-169: 516: 32.91