HitPredict

Interactor 1: LRP2 (A2ARV4)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Interactor 2: ARH (Q8C142)
Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog)
Gene: Ldlrap1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23836931
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030424 - axon GO:0050750 - low-density lipoprotein particle receptor binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4660 Mm			1 308
+	Rn
		88518 LRP2_RAT (1-4660): 0: 3822: 93.88		ARH_RAT (1-308): 4.36e-95: 285: 95.78
+	Hs
		957612 LRP2_HUMAN (1-4660): 0: 3724: 76.61		ARH_HUMAN (1-308): 5.54e-100: 297: 89.32
+	Mm
		57553 LRP2_MOUSE (1-4660): 0: 3809: 100.00		DAB1_MOUSE (43-302): 5.99e-50: 176: 19.27
+	Rn
		292326 LRP2_RAT (1-4660): 0: 3822: 93.88		DAB2_RAT (8-307): 2.34e-43: 160: 15.14
+	Mm
		57554 LRP2_MOUSE (1-4660): 0: 3809: 100.00		DAB2_MOUSE (8-307): 4.96e-44: 162: 15.46
+	Hs
		957621 LRP2_HUMAN (1-4660): 0: 3724: 76.61		ANS1B_HUMAN (13-230): 1.28e-50: 181: 22.07
+	Hs
		253552 LRP2_HUMAN (1-4660): 0: 3724: 76.61		CAPON_HUMAN (34-300): 7.68e-52: 179: 22.92
+	Hs
		269134 LRP2_HUMAN (1-4660): 0: 3724: 76.61		DAB1_HUMAN (43-302): 3.81e-51: 179: 20.51
+	Mm
		57563 LRP2_MOUSE (1-4660): 0: 3809: 100.00		JIP1_MOUSE (47-169): 9.78e-16: 79.5: 21.21
+	Hs
		957165 LRP2_HUMAN (1-4660): 0: 3724: 76.61		DAB2_HUMAN (8-307): 1.37e-42: 157: 15.46
+	Hs
		957662 LRP2_HUMAN (1-4660): 0: 3724: 76.61		JIP1_HUMAN (47-169): 1.45e-15: 79.1: 21.21
+	Hs
		351073 LDLR_HUMAN (2603-2890): 1.14e-15: 86.8: 18.90		ARH_HUMAN (1-308): 5.54e-100: 297: 89.32
+	Hs
		269114 LDLR_HUMAN (2603-2890): 1.14e-15: 86.8: 18.90		DAB1_HUMAN (43-302): 3.81e-51: 179: 20.51
+	Hs
		253558 LRP8_HUMAN (3435-3651): 6.7e-14: 81: 22.59		CAPON_HUMAN (34-300): 7.68e-52: 179: 22.92
+	Hs
		269145 LRP8_HUMAN (3435-3651): 6.7e-14: 81: 22.59		DAB1_HUMAN (43-302): 3.81e-51: 179: 20.51
+	Ce
		60773 LRP_CAEEL (212-617): 7.12e-11: 71.4: 17.41		A5JYR4_CAEEL (5-303): 1.09e-54: 186: 18.15
+	Hs
		351065 LDLR_HUMAN (2603-2890): 1.14e-15: 86.8: 18.90		DAB2_HUMAN (8-307): 1.37e-42: 157: 15.46
+	Hs
		957177 LRP8_HUMAN (3435-3651): 6.7e-14: 81: 22.59		DAB2_HUMAN (8-307): 1.37e-42: 157: 15.46
+	Hs
		1048463 LRP8_HUMAN (3435-3651): 6.7e-14: 81: 22.59		JIP1_HUMAN (47-169): 1.45e-15: 79.1: 21.21
+	Mm
		1257662 LRP4_MOUSE (927-1144): 2.82e-13: 79.5: 16.07		JIP1_MOUSE (47-169): 9.78e-16: 79.5: 21.21