HitPredict

Interactor 1: LRP2 (A2ARV4)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Interactor 2: SYJ2B (Q9D6K5)
Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Activin receptor-interacting protein 4) (Mitochondrial outer membrane protein 25)
Gene: Synj2bp

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	10827173
Identification Methods	two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0009986 - cell surface
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 4660 Mm			1 145
+	Mm
		57555 LRP2_MOUSE (1-4660): 0: 3809: 100.00		DLG4_MOUSE (3-135): 9.49e-28: 108: 30.83
+	Hs
		883907 LRP2_HUMAN (1-4660): 0: 3724: 76.61		SYJ2B_HUMAN (1-145): 1.53e-48: 154: 91.03
+	Hs
		957608 LRP2_HUMAN (1-4660): 0: 3724: 76.61		DLG2_HUMAN (6-140): 8.2e-28: 109: 31.11
+	Hs
		942324 LRP2_HUMAN (1-4660): 0: 3724: 76.61		DLG4_HUMAN (3-135): 9.13e-28: 108: 30.83
+	Hs
		957631 LRP2_HUMAN (1-4660): 0: 3724: 76.61		DLG3_HUMAN (1-117): 5.97e-24: 98.1: 41.03
+	Hs
		883911 LRP8_HUMAN (3435-3651): 6.7e-14: 81: 22.59		SYJ2B_HUMAN (1-145): 1.53e-48: 154: 91.03
+	Mm
		1265297 LRP1_MOUSE (233-464): 3.78e-09: 66: 11.21		SYJ2B_MOUSE (1-145): 2.64e-48: 153: 100.00
+	Hs
		883908 LRP1_HUMAN (3714-3975): 8.74e-09: 64.5: 11.36		SYJ2B_HUMAN (1-145): 1.53e-48: 154: 91.03
+	Hs
		942339 LRP8_HUMAN (3435-3651): 6.7e-14: 81: 22.59		DLG4_HUMAN (3-135): 9.13e-28: 108: 30.83
+	Mm
		1267815 LRP1B_MOUSE (3825-4079): 8.05e-09: 64.9: 14.62		SNTG2_MOUSE (3-144): 2.72e-33: 123: 24.68
+	Dm
		113371 Q9VBN2_DROME (940-1135): 2.3e-09: 66: 17.00		M9NFI9_DROME (14-109): 5.35e-29: 112: 31.96
+	Dm
		113773 Q9W4Y3_DROME (17-65): 3.41e-09: 65.9: 42.86		M9NFI9_DROME (14-109): 5.35e-29: 112: 31.96
+	Mm
		57225 NID1_MOUSE (2610-2847): 6.32e-09: 64.8: 11.60		A2AKD7_MOUSE (1-141): 2.12e-29: 113: 23.08
+	Mm
		1143476 LRP8_MOUSE (3874-4066): 3.48e-10: 68.7: 24.23		DLG4_MOUSE (3-135): 9.49e-28: 108: 30.83
+	Mm
		69882 B1AXJ3_MOUSE (940-1144): 1.76e-09: 66.4: 15.35		DLG4_MOUSE (3-135): 9.49e-28: 108: 30.83
+	Mm
		1143471 LRP1_MOUSE (233-464): 3.78e-09: 66: 11.21		DLG4_MOUSE (3-135): 9.49e-28: 108: 30.83
+	Hs
		942331 LRP1_HUMAN (3714-3975): 8.74e-09: 64.5: 11.36		DLG4_HUMAN (3-135): 9.13e-28: 108: 30.83