HitPredict

Interactor 1: VINC (P18206)
Vinculin (Metavinculin) (MV)
Gene: VCL

Interactor 2: CADH5 (P33151)
Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
Gene: CDH5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26923917
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0005912 - adherens junction GO:0008013 - beta-catenin binding GO:0035633 - maintenance of blood-brain barrier and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1134 Hs			1 784
+	Hs
		521714 VINC_HUMAN (1-1134): 0: 893: 100.00		CADH1_HUMAN (26-780): 0: 590: 31.71
+	Hs
		640703 CTNA2_HUMAN (5-805): 6.26e-76: 272: 16.03		CADH5_HUMAN (1-784): 0: 794: 100.00
+	Hs
		702744 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		CADH5_HUMAN (1-784): 0: 794: 100.00
+	Mm
		640688 CTNA1_MOUSE (5-899): 1.14e-64: 238: 15.48		CADH5_MOUSE (1-783): 0: 750: 74.68
+	Hs
		716725 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		CAD24_HUMAN (1-782): 0: 684: 35.90
+	Hs
		1199809 CTNA3_HUMAN (5-886): 1.19e-63: 235: 12.92		CAD24_HUMAN (1-782): 0: 684: 35.90
+	Hs
		521735 CTNA2_HUMAN (5-805): 6.26e-76: 272: 16.03		CADH1_HUMAN (26-780): 0: 590: 31.71
+	Hs
		521757 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		CADH1_HUMAN (26-780): 0: 590: 31.71
+	Hs
		522254 CTNA3_HUMAN (5-886): 1.19e-63: 235: 12.92		CADH1_HUMAN (26-780): 0: 590: 31.71
+	Mm
		454942 CTNA1_MOUSE (5-899): 1.14e-64: 238: 15.48		CADH1_MOUSE (25-780): 0: 582: 30.99
+	Hs
		606300 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		CADH3_HUMAN (32-780): 0: 574: 30.49
+	Hs
		606311 CTNA3_HUMAN (5-886): 1.19e-63: 235: 12.92		CADH3_HUMAN (32-780): 0: 574: 30.49
+	Hs
		640714 CTNA2_HUMAN (5-805): 6.26e-76: 272: 16.03		CAD12_HUMAN (1-469): 7.9e-89: 298: 23.46
+	Hs
		640713 CTNA2_HUMAN (5-805): 6.26e-76: 272: 16.03		CADH8_HUMAN (1-469): 2.58e-86: 292: 22.75
+	Hs
		716641 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		CAD12_HUMAN (1-469): 7.9e-89: 298: 23.46
+	Hs
		716640 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		CADH8_HUMAN (1-469): 2.58e-86: 292: 22.75
+	Hs
		877559 CTNA3_HUMAN (5-886): 1.19e-63: 235: 12.92		CAD12_HUMAN (1-469): 7.9e-89: 298: 23.46
+	Hs
		877527 CTNA3_HUMAN (5-886): 1.19e-63: 235: 12.92		CADH4_HUMAN (1-475): 6.52e-65: 235: 19.88
+	Hs
		580206 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		CADH2_HUMAN (1-469): 4.36e-61: 224: 20.67
+	Hs
		580266 CTNA3_HUMAN (5-886): 1.19e-63: 235: 12.92		CADH2_HUMAN (1-469): 4.36e-61: 224: 20.67