Interactor 1: VINC (P18206)
Vinculin (Metavinculin) (MV)
Gene: VCL

Interactor 2: TLN1 (Q9Y490)
Talin-1
Gene: TLN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.908

The method score is based on:

Property Details
Experiments 26496610, 18056416, 26923917, 35271311
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains VBS~Vinculin
Common GO terms GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1134
Hs

1 2541
+ Mm
+ Gg
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024