HitPredict

Interactor 1: RD21L (A2AU37)
Double-strand-break repair protein rad21-like protein 1
Gene: Rad21l1

Interactor 2: SMC1B (Q920F6)
Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B)
Gene: SMC1B

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.712

Property	Details
Experiments	24797474, 24797475
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Rad21_Rec8~SMC_N, Rad21_Rec8_N~SMC_N
Common GO terms	GO:0000794 - condensed nuclear chromosome GO:0000800 - lateral element GO:0005634 - nucleus GO:0007062 - sister chromatid cohesion GO:0030893 - meiotic cohesin complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 552 Mm			1 1248
+	Mm
		57598 RD21L_MOUSE (1-552): 0: 630: 100.00		SMC1A_MOUSE (1-1222): 3.79e-110: 376: 52.16
+	Mm
		1142818 RAD21_MOUSE (1-550): 7.47e-178: 517: 39.94		SMC1B_MOUSE (1-1248): 3.75e-118: 399: 100.00
+	Hs
		224479 RAD21_HUMAN (1-550): 0: 525: 40.41		SMC1B_HUMAN (1-1234): 4.05e-113: 385: 83.32
+	Hs
		224434 RAD21_HUMAN (1-550): 0: 525: 40.41		SMC1A_HUMAN (1-1222): 5.62e-110: 376: 52.08
+	Mm
		57599 RD21L_MOUSE (1-552): 0: 630: 100.00		SMC3_MOUSE (3-1226): 6.48e-72: 265: 15.50
+	Mm
		1142821 RAD21_MOUSE (1-550): 7.47e-178: 517: 39.94		SMC1A_MOUSE (1-1222): 3.79e-110: 376: 52.16
+	Xl
		292726 RAD21_XENLA (1-552): 1.56e-178: 519: 40.79		SMC1A_XENLA (1-1222): 7.05e-105: 362: 52.57
+	Hs
		224536 RAD21_HUMAN (1-550): 0: 525: 40.41		SMC4_HUMAN (4-1217): 8.29e-79: 286: 19.09
+	Xl
		1150103 Q6DCL7_XENLA (1-550): 0: 525: 41.24		Q8AW91_XENLA (3-1226): 9.73e-72: 264: 15.34
+	Hs
		224554 RAD21_HUMAN (1-550): 0: 525: 40.41		SMC3_HUMAN (3-1226): 8.19e-72: 264: 15.50
+	Xl
		292737 RAD21_XENLA (1-552): 1.56e-178: 519: 40.79		SMC3_XENLA (3-1226): 1.92e-72: 266: 15.44
+	Xl
		292746 RAD21_XENLA (1-552): 1.56e-178: 519: 40.79		Q8AW91_XENLA (3-1226): 9.73e-72: 264: 15.34
+	Mm
		1142822 RAD21_MOUSE (1-550): 7.47e-178: 517: 39.94		SMC3_MOUSE (3-1226): 6.48e-72: 265: 15.50
+	Hs
		224250 RAD21_HUMAN (1-550): 0: 525: 40.41		SMC2_HUMAN (3-1227): 2.15e-68: 254: 15.97
+	Mm
		1207969 REC8_MOUSE (1-549): 2.2e-114: 353: 17.84		SMC1B_MOUSE (1-1248): 3.75e-118: 399: 100.00
+	Hs
		304446 REC8_HUMAN (1-550): 5.03e-116: 356: 17.89		SMC1B_HUMAN (1-1234): 4.05e-113: 385: 83.32
+	Hs
		304438 REC8_HUMAN (1-550): 5.03e-116: 356: 17.89		SMC1A_HUMAN (1-1222): 5.62e-110: 376: 52.08
+	Sp
		293281 REC8_SCHPO (1-544): 6.73e-115: 353: 15.65		SMC1_SCHPO (1-1220): 2.62e-75: 275: 29.42
+	Sp
		193874 REC8_SCHPO (1-544): 6.73e-115: 353: 15.65		SMC3_SCHPO (3-1220): 6.48e-75: 273: 15.21
+	Hs
		304460 REC8_HUMAN (1-550): 5.03e-116: 356: 17.89		SMC3_HUMAN (3-1226): 8.19e-72: 264: 15.50