HitPredict

Interactor 1: SGG (P18431)
Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white 3)
Gene: SGG

Interactor 2: Q400N1 (Q400N1)
FI22203p1 (Pericentrin-like protein, isoform C)
Gene: Plp

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	21447707, 25294943
Identification Methods	affinity chromatography technology, interactome parallel affinity capture, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0007165 - signal transduction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 514 Dm			1 1109
+	Dm
		576488 SGG_DROME (1-514): 6.06e-152: 445: 100.00		MYSN_DROME (4-960): 1.78e-32: 139: 14.17
+	Dm
		576356 SGG_DROME (1-514): 6.06e-152: 445: 100.00		Q59E58_DROME (87-967): 5.22e-29: 128: 13.94
+	Hs
		960129 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH13_HUMAN (82-1039): 1.81e-40: 165: 12.11
+	Hs
		528401 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		MYH8_HUMAN (412-1084): 2.76e-26: 119: 11.75
+	Hs
		625177 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		MYH10_HUMAN (1-672): 1.66e-25: 116: 12.48
+	Hs
		835802 GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94		GRDN_HUMAN (1-661): 5.04e-25: 115: 10.91
+	Dm
		576384 SGG_DROME (1-514): 6.06e-152: 445: 100.00		Q7K523_DROME (350-955): 4.49e-17: 89.5: 17.85
+	Dm
		576635 SGG_DROME (1-514): 6.06e-152: 445: 100.00		CL190_DROME (1-445): 2.25e-15: 83.6: 12.78
+	Hs
		528405 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH8_HUMAN (412-1084): 2.76e-26: 119: 11.75
+	Hs
		835390 GSK3A_HUMAN (19-419): 1.05e-137: 408: 70.57		GRDN_HUMAN (1-661): 5.04e-25: 115: 10.91
+	Hs
		960128 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH2_HUMAN (398-1063): 2.06e-25: 116: 9.87
+	Hs
		522542 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH1_HUMAN (386-1063): 1.31e-23: 110: 10.50
+	Hs
		625176 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		MYH9_HUMAN (638-1028): 3.57e-15: 83.2: 9.90
+	Hs
		724714 GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94		MYH9_HUMAN (638-1028): 3.57e-15: 83.2: 9.90
+	Hs
		625530 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		MY18A_HUMAN (1-485): 5.39e-12: 72.7: 12.09
+	Hs
		522604 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH7_HUMAN (520-1013): 2.68e-18: 93.3: 10.40
+	Hs
		528368 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH6_HUMAN (578-1041): 2.52e-17: 90.2: 11.37
+	Hs
		551610 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		DESP_HUMAN (336-915): 7.88e-09: 62.5: 13.75
+	Hs
		502908 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH3_HUMAN (609-1070): 2.74e-15: 83.6: 13.21