HitPredict

Interactor 1: A2AWT7 (A2AWT7)
Upstream binding transcription factor, RNA polymerase I
Gene: Ubtf

Interactor 2: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	16582105
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 752 Mm			1 482
+	Hs
		567691 UBF1_HUMAN (1-638): 4.58e-155: 471: 93.78		HDAC1_HUMAN (1-482): 0: 666: 99.38
+	Hs
		331809 NSD2_HUMAN (194-625): 2.74e-33: 140: 13.77		HDAC1_HUMAN (1-482): 0: 666: 99.38
+	Hs
		331858 NSD2_HUMAN (194-625): 2.74e-33: 140: 13.77		HDAC2_HUMAN (1-478): 0: 664: 86.13
+	Hs
		1038602 SMCE1_HUMAN (116-373): 8.08e-30: 124: 15.67		HDAC1_HUMAN (1-482): 0: 666: 99.38
+	Hs
		1270357 SMCE1_HUMAN (116-373): 8.08e-30: 124: 15.67		HDAC2_HUMAN (1-478): 0: 664: 86.13
+	Hs
		1038736 HM20A_HUMAN (91-289): 1.81e-28: 119: 17.33		HDAC1_HUMAN (1-482): 0: 666: 99.38
+	Hs
		1270459 HM20A_HUMAN (91-289): 1.81e-28: 119: 17.33		HDAC2_HUMAN (1-478): 0: 664: 86.13
+	Hs
		1038764 HM20B_HUMAN (331-514): 2.61e-27: 115: 15.76		HDAC1_HUMAN (1-482): 0: 666: 99.38
+	Hs
		1270484 HM20B_HUMAN (331-514): 2.61e-27: 115: 15.76		HDAC2_HUMAN (1-478): 0: 664: 86.13
+	Mm
		140241 SOX2_MOUSE (333-453): 3.18e-23: 103: 17.36		HDAC1_MOUSE (1-482): 0: 670: 100.00
+	Mm
		140273 Q60I23_MOUSE (333-453): 2.1e-23: 103: 17.36		HDAC1_MOUSE (1-482): 0: 670: 100.00
+	Hs
		818023 SOX2_HUMAN (332-453): 7.78e-24: 105: 16.39		HDAC1_HUMAN (1-482): 0: 666: 99.38
+	Hs
		818314 SOX2_HUMAN (332-453): 7.78e-24: 105: 16.39		HDAC2_HUMAN (1-478): 0: 664: 86.13
+	Mm
		818688 SOX2_MOUSE (333-453): 3.18e-23: 103: 17.36		HDAC2_MOUSE (1-478): 0: 663: 85.92
+	Mm
		936399 Q60I23_MOUSE (333-453): 2.1e-23: 103: 17.36		HDAC2_MOUSE (1-478): 0: 663: 85.92
+	Hs
		727863 SOX6_HUMAN (287-476): 6.93e-19: 93.6: 14.21		HDAC1_HUMAN (1-482): 0: 666: 99.38
+	Hs
		177229 SOX2_HUMAN (332-453): 7.78e-24: 105: 16.39		HDAC3_HUMAN (9-434): 0: 572: 58.18
+	Mm
		1142019 Q60I23_MOUSE (333-453): 2.1e-23: 103: 17.36		Q9JM08_MOUSE (9-434): 0: 566: 57.94
+	Hs
		177214 SOX6_HUMAN (287-476): 6.93e-19: 93.6: 14.21		HDAC3_HUMAN (9-434): 0: 572: 58.18
+	Hs
		996942 SSRP1_HUMAN (143-384): 3.5e-19: 94.3: 15.29		HDAC6_HUMAN (16-325): 3.43e-93: 308: 25.78