HitPredict

Interactor 1: SGG (P18431)
Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white 3)
Gene: SGG

Interactor 2: EIF3A (Q9VN25)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10)
Gene: EIF3A

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	21447707, 25294943
Identification Methods	affinity chromatography technology, interactome parallel affinity capture, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 514 Dm			1 1140
+	Hs
		625425 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		EIF3A_HUMAN (1-1056): 2.97e-107: 368: 44.54
+	Hs
		835745 GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94		EIF3A_HUMAN (1-1056): 2.97e-107: 368: 44.54
+	Hs
		835368 GSK3A_HUMAN (19-419): 1.05e-137: 408: 70.57		EIF3A_HUMAN (1-1056): 2.97e-107: 368: 44.54
+	Hs
		528368 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH6_HUMAN (167-1140): 1.15e-46: 185: 10.26
+	Hs
		835653 GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94		MAP1A_HUMAN (477-1026): 2.7e-38: 158: 12.90
+	Hs
		625176 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		MYH9_HUMAN (344-1137): 1.51e-34: 146: 9.54
+	Hs
		724714 GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94		MYH9_HUMAN (344-1137): 1.51e-34: 146: 9.54
+	Hs
		835321 GSK3A_HUMAN (19-419): 1.05e-137: 408: 70.57		MAP1A_HUMAN (477-1026): 2.7e-38: 158: 12.90
+	Hs
		625177 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		MYH10_HUMAN (104-1036): 7.81e-29: 127: 10.22
+	Hs
		528401 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		MYH8_HUMAN (165-1072): 1.61e-28: 126: 10.10
+	Hs
		502908 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH3_HUMAN (386-1137): 2.96e-27: 122: 8.49
+	Hs
		835516 GSK3A_HUMAN (19-419): 1.05e-137: 408: 70.57		WDR33_HUMAN (904-1140): 5.37e-26: 118: 21.72
+	Hs
		522542 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH1_HUMAN (85-1000): 1.42e-26: 120: 8.88
+	Dm
		116374 SGG_DROME (1-514): 6.06e-152: 445: 100.00		M9PI41_DROME (503-903): 1.61e-11: 71: 16.59
+	Dm
		576747 SGG_DROME (1-514): 6.06e-152: 445: 100.00		Q9VTY8_DROME (503-903): 1.64e-11: 71: 16.59
+	Dm
		576838 SGG_DROME (1-514): 6.06e-152: 445: 100.00		Q9W053_DROME (310-749): 6.16e-09: 62.7: 12.83
+	Hs
		625446 CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23		PLEC_HUMAN (504-1001): 1.39e-12: 75: 10.16
+	Hs
		835769 GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94		PLEC_HUMAN (504-1001): 1.39e-12: 75: 10.16
+	At
		98147 KSG7_ARATH (16-394): 1.2e-148: 432: 57.63		F4JPR4_ARATH (583-1024): 5.03e-09: 63: 13.56
+	Hs
		522604 CDK3_HUMAN (51-355): 9.94e-139: 404: 31.63		MYH7_HUMAN (82-736): 9.35e-15: 81.9: 8.94