HitPredict

Interactor 1: PTPRA (P18433)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)
Gene: PTPRA

Interactor 2: HUNK (P57058)
Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)
Gene: HUNK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 714
+	Hs
		616967 PTPRD_HUMAN (38-799): 0: 897: 40.50		HUNK_HUMAN (1-714): 0: 641: 100.00
+	Hs
		577034 PTPRA_HUMAN (1-802): 0: 1040: 100.00		MARK2_HUMAN (9-705): 6.35e-146: 446: 22.33
+	Hs
		576986 PTPRA_HUMAN (1-802): 0: 1040: 100.00		MARK3_HUMAN (12-645): 8.19e-141: 432: 23.92
+	Hs
		616987 PTPRD_HUMAN (38-799): 0: 897: 40.50		MARK2_HUMAN (9-705): 6.35e-146: 446: 22.33
+	Hs
		640215 PTN3_HUMAN (520-793): 1.24e-105: 347: 30.82		AKT1_HUMAN (8-379): 8.23e-135: 407: 26.23