HitPredict

Interactor 1: PTPRA (P18433)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)
Gene: PTPRA

Interactor 2: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32062451
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Y_phosphatase~Y_phosphatase
Common GO terms	GO:0004725 - protein tyrosine phosphatase activity GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 2485
+	Hs
		577065 PTPRA_HUMAN (1-802): 0: 1040: 100.00		E41L1_HUMAN (471-1098): 1e-116: 395: 18.37
+	Hs
		576993 PTPRA_HUMAN (1-802): 0: 1040: 100.00		MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65
+	Hs
		616916 PTPRS_HUMAN (5-799): 0: 925: 38.45		PTPRB_HUMAN (953-2481): 3.7e-135: 473: 14.59
+	Hs
		576980 PTPRA_HUMAN (1-802): 0: 1040: 100.00		PTPRA_HUMAN (2194-2468): 1.65e-96: 334: 31.10
+	Mm
		574008 PTPRA_MOUSE (1-802): 0: 1003: 90.69		PTPRD_MOUSE (2189-2468): 9.78e-93: 338: 30.72
+	Hs
		576983 PTPRA_HUMAN (1-802): 0: 1040: 100.00		PTPRE_HUMAN (2186-2468): 8.59e-86: 299: 28.72
+	Mm
		573997 PTPRA_MOUSE (1-802): 0: 1003: 90.69		PTPRA_MOUSE (2194-2468): 2.04e-96: 334: 31.10
+	Mm
		56906 PTPRA_MOUSE (1-802): 0: 1003: 90.69		PTPRF_MOUSE (2222-2468): 6.51e-89: 326: 32.81
+	Mm
		69645 PTPRA_MOUSE (1-802): 0: 1003: 90.69		PTPRS_MOUSE (2157-2468): 9.82e-89: 325: 28.04
+	Mm
		574002 PTPRA_MOUSE (1-802): 0: 1003: 90.69		PTPRE_MOUSE (2186-2468): 1.31e-85: 299: 29.05
+	Mm
		574010 PTPRA_MOUSE (1-802): 0: 1003: 90.69		S4R1M0_MOUSE (2199-2479): 7.03e-70: 260: 25.79
+	Hs
		1031977 PTPRS_HUMAN (5-799): 0: 925: 38.45		PTPRS_HUMAN (1007-2468): 3.28e-92: 337: 12.77
+	Hs
		616971 PTPRS_HUMAN (5-799): 0: 925: 38.45		PTPRD_HUMAN (2189-2468): 1.65e-92: 337: 30.72
+	Hs
		489957 PTPRS_HUMAN (5-799): 0: 925: 38.45		PTPRF_HUMAN (2189-2468): 4.55e-89: 326: 30.38
+	Mm
		573998 PTPRA_MOUSE (1-802): 0: 1003: 90.69		PTPRM_MOUSE (2186-2471): 2.06e-58: 226: 24.92
+	Mm
		69646 PTPRS_MOUSE (5-799): 0: 930: 38.96		PTPRE_MOUSE (2186-2468): 1.31e-85: 299: 29.05
+	Hs
		576984 PTPRA_HUMAN (1-802): 0: 1040: 100.00		PTPRG_HUMAN (2228-2472): 1.03e-46: 187: 25.87
+	Mm
		69654 PTPRS_MOUSE (5-799): 0: 930: 38.96		S4R1M0_MOUSE (2199-2479): 7.03e-70: 260: 25.79