HitPredict

Interactor 1: AP2A2 (P18484)
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene: AP2A2

Interactor 2: ITM2B (Q5XIE8)
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]
Gene: ITM2B

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29476059
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 938 Rn			1 266
+	Rn
		1140245 Q66HM2_RAT (1-938): 0: 890: 99.57		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Hs
		321675 AP2A1_HUMAN (1-938): 0: 834: 78.37		ITM2B_HUMAN (1-266): 1.32e-148: 417: 96.24
+	Rn
		923856 AP2B1_RAT (36-933): 0: 628: 16.58		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		854017 AP1B1_RAT (36-929): 0: 604: 16.55		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Hs
		1377119 COPG1_HUMAN (18-930): 0: 580: 13.59		ITM2B_HUMAN (1-266): 1.32e-148: 417: 96.24