HitPredict

Interactor 1: SYB (P18489)
Synaptobrevin
Gene: SYB

Interactor 2: Q9VH76 (Q9VH76)
Synaptosomal-associated protein
Gene: Snap24

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	15710747, 22036573
Identification Methods	two hybrid, affinity chromatography technology, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0007269 - neurotransmitter secretion GO:0016192 - vesicle-mediated transport GO:0019905 - syntaxin binding and 1 others more... GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Dm			1 212
+	Dm
		577212 SYB_DROME (1-152): 8.51e-56: 173: 100.00		SNP25_DROME (9-211): 5.69e-60: 188: 71.92
+	Dm
		1178123 Q7JYX5_DROME (23-127): 1.45e-36: 126: 16.82		Q9VH76_DROME (1-212): 4.78e-71: 216: 100.00
+	Dm
		577265 SYB_DROME (1-152): 8.51e-56: 173: 100.00		Q9W1I8_DROME (7-211): 4.67e-49: 163: 24.00
+	Dm
		115829 M9PGI6_DROME (3-128): 1.23e-31: 113: 16.67		Q9VH76_DROME (1-212): 4.78e-71: 216: 100.00
+	At
		812701 VA722_ARATH (23-112): 2.31e-40: 136: 29.03		SNP33_ARATH (13-211): 1.29e-55: 180: 27.27
+	At
		1351793 VA721_ARATH (23-112): 6.25e-40: 135: 27.96		SNP33_ARATH (13-211): 1.29e-55: 180: 27.27
+	Dm
		739423 Q7JYX5_DROME (23-127): 1.45e-36: 126: 16.82		SNP25_DROME (9-211): 5.69e-60: 188: 71.92
+	Hs
		263128 SC22B_HUMAN (3-131): 1.41e-37: 129: 20.61		SNP29_HUMAN (7-209): 1.21e-57: 184: 23.77
+	Dm
		115797 M9PGI6_DROME (3-128): 1.23e-31: 113: 16.67		SNP25_DROME (9-211): 5.69e-60: 188: 71.92
+	Hs
		117995 VAMP7_HUMAN (23-112): 1.58e-29: 108: 26.09		SNP23_HUMAN (14-212): 1.21e-61: 192: 47.81
+	Rn
		893314 VAMP1_RAT (18-120): 1.79e-31: 110: 56.31		SNP25_RAT (5-212): 2.01e-59: 187: 58.65
+	Rn
		250770 VAMP2_RAT (41-117): 6.71e-31: 108: 74.03		SNP23_RAT (14-212): 1.41e-59: 187: 51.71
+	Hs
		850549 VAMP7_HUMAN (23-112): 1.58e-29: 108: 26.09		SNP25_HUMAN (5-212): 2.01e-59: 187: 58.65
+	Rn
		893307 VAMP2_RAT (41-117): 6.71e-31: 108: 74.03		SNP25_RAT (5-212): 2.01e-59: 187: 58.65
+	Rn
		893316 VAMP7_RAT (23-113): 1.16e-29: 108: 25.81		SNP25_RAT (5-212): 2.01e-59: 187: 58.65
+	Hs
		320281 VAMP7_HUMAN (23-112): 1.58e-29: 108: 26.09		SNP29_HUMAN (7-209): 1.21e-57: 184: 23.77
+	Hs
		180779 YKT6_HUMAN (1-101): 4.73e-29: 107: 21.78		SNP29_HUMAN (7-209): 1.21e-57: 184: 23.77
+	Dm
		1178141 Q7JYX5_DROME (23-127): 1.45e-36: 126: 16.82		Q9W1I8_DROME (7-211): 4.67e-49: 163: 24.00
+	Dm
		115849 M9PGI6_DROME (3-128): 1.23e-31: 113: 16.67		Q9W1I8_DROME (7-211): 4.67e-49: 163: 24.00
+	Sc
		605850 SEC22_YEAST (3-129): 2.65e-33: 118: 19.38		SEC9_YEAST (12-206): 1.75e-32: 125: 19.28