HitPredict

Interactor 1: SYB (P18489)
Synaptobrevin
Gene: SYB

Interactor 2: Q9W0N6 (Q9W0N6)
LD27967p (Vesicle transport through interaction with t-SNAREs 1a)
Gene: Vti1a

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Synaptobrevin~V-SNARE_C
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0006906 - vesicle fusion GO:0016192 - vesicle-mediated transport GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Dm			1 230
+	Dm
		577252 SYB_DROME (1-152): 8.51e-56: 173: 100.00		GOSR2_DROME (4-218): 1.17e-49: 163: 18.52
+	Dm
		1178140 Q7JYX5_DROME (23-127): 1.45e-36: 126: 16.82		Q9W0N6_DROME (1-225): 9.57e-59: 186: 100.00
+	Rn
		192340 SC22B_RAT (3-131): 1.41e-37: 129: 20.61		GOSR2_RAT (4-218): 1.01e-54: 176: 17.67
+	Hs
		151536 SC22B_HUMAN (3-131): 1.41e-37: 129: 20.61		GOSR2_HUMAN (4-218): 1.04e-53: 173: 16.74
+	Hs
		263321 SC22B_HUMAN (3-131): 1.41e-37: 129: 20.61		VTI1A_HUMAN (2-218): 9.83e-54: 173: 36.41
+	Dm
		115847 M9PGI6_DROME (3-128): 1.23e-31: 113: 16.67		Q9W0N6_DROME (1-225): 9.57e-59: 186: 100.00
+	At
		221565 VA711_ARATH (23-130): 5.39e-33: 117: 21.82		VTI11_ARATH (2-221): 4.05e-57: 182: 28.64
+	Dm
		1178131 Q7JYX5_DROME (23-127): 1.45e-36: 126: 16.82		GOSR2_DROME (4-218): 1.17e-49: 163: 18.52
+	Rn
		1144366 VAMP1_RAT (18-120): 1.79e-31: 110: 56.31		VTI1A_RAT (2-219): 2.66e-55: 178: 35.62
+	Hs
		263387 SC22B_HUMAN (3-131): 1.41e-37: 129: 20.61		VTI1B_HUMAN (2-220): 8.02e-45: 151: 22.97
+	Hs
		151535 VAMP4_HUMAN (30-115): 8.22e-29: 104: 30.23		GOSR2_HUMAN (4-218): 1.04e-53: 173: 16.74
+	Hs
		261703 VAMP4_HUMAN (30-115): 8.22e-29: 104: 30.23		VTI1A_HUMAN (2-218): 9.83e-54: 173: 36.41
+	Dm
		115839 M9PGI6_DROME (3-128): 1.23e-31: 113: 16.67		GOSR2_DROME (4-218): 1.17e-49: 163: 18.52
+	Mm
		291513 VAMP7_MOUSE (23-112): 1.19e-29: 108: 26.09		VTI1B_MOUSE (2-220): 2.43e-51: 168: 23.87
+	Hs
		1284295 VAMP8_HUMAN (40-115): 1.06e-27: 100: 30.26		VTI1A_HUMAN (2-218): 9.83e-54: 173: 36.41
+	Hs
		850604 VAMP7_HUMAN (23-112): 1.58e-29: 108: 26.09		VTI1B_HUMAN (2-220): 8.02e-45: 151: 22.97
+	Hs
		261737 VAMP4_HUMAN (30-115): 8.22e-29: 104: 30.23		VTI1B_HUMAN (2-220): 8.02e-45: 151: 22.97
+	Hs
		1313462 VAMP8_HUMAN (40-115): 1.06e-27: 100: 30.26		VTI1B_HUMAN (2-220): 8.02e-45: 151: 22.97
+	Sc
		605872 SEC22_YEAST (3-129): 2.65e-33: 118: 19.38		VTI1_YEAST (2-202): 9.42e-36: 127: 28.57
+	Sc
		704536 SNC2_YEAST (18-115): 6.95e-29: 103: 29.59		VTI1_YEAST (2-202): 9.42e-36: 127: 28.57