HitPredict

Interactor 1: EMC (P18491)
Protein extra-macrochaetae
Gene: EMC

Interactor 2: Q9W4I4 (Q9W4I4)
Helix loop helix protein 4C, isoform A (IP01307p)
Gene: HLH4C

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.80	0.587

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 199 Dm			1 167
+	Hs
		551480 ID4_HUMAN (38-103): 2.02e-31: 113: 41.25		TFE2_HUMAN (5-165): 8.69e-26: 104: 19.75
+	Hs
		814916 ID4_HUMAN (38-103): 2.02e-31: 113: 41.25		NGN3_HUMAN (40-165): 4.46e-25: 97.6: 25.36
+	Hs
		551478 ID1_HUMAN (38-99): 7.16e-29: 106: 47.76		TFE2_HUMAN (5-165): 8.69e-26: 104: 19.75
+	Hs
		814906 ID4_HUMAN (38-103): 2.02e-31: 113: 41.25		OLIG2_HUMAN (31-165): 2.18e-23: 95.6: 21.43
+	Hs
		780960 ID1_HUMAN (38-99): 7.16e-29: 106: 47.76		HEN2_HUMAN (29-165): 3.67e-25: 95.7: 41.30
+	Hs
		551502 ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67		TFE2_HUMAN (5-165): 8.69e-26: 104: 19.75
+	Hs
		568188 ID4_HUMAN (38-103): 2.02e-31: 113: 41.25		TAL1_HUMAN (107-165): 5.35e-18: 80.9: 54.24
+	Hs
		970566 ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67		OLIG2_HUMAN (31-165): 2.18e-23: 95.6: 21.43
+	Hs
		238590 ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67		MUSC_HUMAN (31-165): 3.38e-24: 95.3: 22.14
+	Hs
		524549 ID4_HUMAN (38-103): 2.02e-31: 113: 41.25		LYL1_HUMAN (107-165): 1.4e-16: 76.7: 52.54
+	Mm
		589139 ID1_MOUSE (38-99): 5.12e-29: 107: 47.76		TAL1_MOUSE (107-165): 8.8e-18: 80.5: 54.24
+	Hs
		551503 ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67		TFE2_HUMAN (5-165): 8.69e-26: 104: 19.75
+	Hs
		524547 ID1_HUMAN (38-99): 7.16e-29: 106: 47.76		LYL1_HUMAN (107-165): 1.4e-16: 76.7: 52.54
+	Hs
		524557 ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67		LYL1_HUMAN (107-165): 1.4e-16: 76.7: 52.54