HitPredict

Interactor 1: PTC (P18502)
Protein patched (Hedgehog receptor)
Gene: PTC

Interactor 2: PTC (P18502)
Protein patched (Hedgehog receptor)
Gene: PTC

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.898

The method score is based on:

Property Details
Experiments 10983992, 16980583, 17284519, 15710747
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Patched~Patched
Common GO terms GO:0001746 - Bolwig's organ morphogenesis
GO:0005119 - smoothened binding
GO:0005886 - plasma membrane
GO:0005929 - cilium
GO:0007346 - regulation of mitotic cell cycle
and 20 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1286
Dm

1 1286
+ Hs
+ Hs
+ Hs
+ Pa
+ Ec
+ Ec
+ Ec
+ Ec
+ Ec
+ Ec
+ Bs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024