HitPredict

Interactor 1: SON (P18583)
Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3)
Gene: SON

Interactor 2: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.616

Property	Details
Experiments	33961781, 32707033, 23602568
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2426 Hs			1 567
+	Hs
		577617 SON_HUMAN (1-2426): 0: 655: 100.00		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		577604 SON_HUMAN (1-2426): 0: 655: 100.00		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		577687 SON_HUMAN (1-2426): 0: 655: 100.00		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Hs
		1304770 SCAFB_HUMAN (1309-2042): 9.77e-17: 89.6: 16.07		SRPK3_HUMAN (27-567): 5.16e-140: 418: 100.00
+	Hs
		1037914 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		SRPK3_HUMAN (27-567): 5.16e-140: 418: 100.00
+	Sp
		736990 THO2_SCHPO (1667-2041): 9.74e-18: 93: 19.30		DSK1_SCHPO (3-565): 8.43e-109: 338: 35.27
+	At
		1105844 Q9SKR5_ARATH (1800-2038): 1.56e-41: 167: 26.98		KSG7_ARATH (79-336): 1.55e-72: 238: 16.42
+	Hs
		1082653 MUC12_HUMAN (904-2321): 3.78e-46: 187: 9.01		MK14_HUMAN (66-259): 1.61e-45: 165: 21.78
+	Hs
		942896 SCAFB_HUMAN (1309-2042): 9.77e-17: 89.6: 16.07		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		625528 TITIN_HUMAN (735-1660): 9.25e-11: 70.2: 9.62		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Hs
		942637 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		942845 TITIN_HUMAN (735-1660): 9.25e-11: 70.2: 9.62		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		833876 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		1264773 TITIN_HUMAN (735-1660): 9.25e-11: 70.2: 9.62		DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82
+	Hs
		311795 TACC2_HUMAN (3-1233): 8.43e-12: 73.4: 9.06		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		1037873 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Dm
		834215 Q9W1A9_DROME (988-1900): 2.02e-31: 138: 11.67		DOA_DROME (396-566): 7.94e-12: 70.1: 25.41
+	Sp
		999904 THO2_SCHPO (1667-2041): 9.74e-18: 93: 19.30		LKH1_SCHPO (404-565): 1.99e-12: 72: 27.81
+	Hs
		834036 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		833730 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		CLK1_HUMAN (405-566): 8.71e-11: 66.2: 26.01