Interactor 1: NELFE (P18615)
Negative elongation factor E (NELF-E) (RNA-binding protein RD)
Gene: NELFE

Interactor 2: NELFB (Q8WX92)
Negative elongation factor B (NELF-B) (Cofactor of BRCA1)
Gene: NELFB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 32296183, 20305087, 26186194, 14667819, 26496610, 28514442, 12612062, 24981860, 33961781, unassigned1304, 20211142
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032021 - NELF complex
GO:0034244 - negative regulation of transcription elongation by RNA polymerase II
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 380
Hs

1 580
+ Dm

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Last updated: 15 Jul 2024