HitPredict

Interactor 1: KS6A3 (P18654)
Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
Gene: Rps6ka3

Interactor 2: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	10862698
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 740 Mm			1 938
+	Mm
		578247 KS6A1_MOUSE (1-740): 0: 754: 76.82		NMDZ1_MOUSE (1-938): 0: 920: 100.00
+	Mm
		578261 KS6A3_MOUSE (1-740): 0: 844: 100.00		NMDE2_MOUSE (4-938): 0: 628: 23.86
+	Mm
		578250 KS6A1_MOUSE (1-740): 0: 754: 76.82		NMDE2_MOUSE (4-938): 0: 628: 23.86
+	Mm
		397201 KAPCA_MOUSE (409-714): 3.01e-115: 353: 28.21		NMDZ1_MOUSE (1-938): 0: 920: 100.00
+	Hs
		616679 KS6B1_HUMAN (411-727): 9.6e-116: 360: 26.27		GRIA1_HUMAN (5-904): 0: 680: 21.77
+	Hs
		568576 KAPCA_HUMAN (409-714): 3.03e-116: 356: 28.84		GRIA1_HUMAN (5-904): 0: 680: 21.77
+	Hs
		568583 KAPCA_HUMAN (409-714): 3.03e-116: 356: 28.84		GRIA4_HUMAN (7-888): 0: 659: 21.72
+	Mm
		620958 AKT2_MOUSE (390-739): 5.95e-126: 385: 24.39		GRIA2_MOUSE (3-856): 0: 628: 21.55
+	Hs
		681815 AKT1_HUMAN (327-739): 7.83e-127: 387: 21.02		NMDE1_HUMAN (1-923): 0: 623: 24.11
+	Mm
		397210 KAPCA_MOUSE (409-714): 3.01e-115: 353: 28.21		NMDE2_MOUSE (4-938): 0: 628: 23.86