Interactor 1: KALRN (A2CG49)
Kalirin (EC 2.7.11.1) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)
Gene: KALRN

Interactor 2: TRIO (Q0KL02)
Triple functional domain protein (EC 2.7.11.1)
Gene: TRIO

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 28706196
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CRAL_TRIO_2~CRAL_TRIO_2, I-set~fn3, Pkinase~fn3, RhoGEF~fn3, I-set~I-set, I-set~Pkinase, PH~PH, PH~Pkinase, PH~RhoGEF, PH~SH3_1, Pkinase~Pkinase, RhoGEF~RhoGEF, RhoGEF~SH3_1, SH3_1~SH3_1, Spectrin~Spectrin
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0007411 - axon guidance
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2964
Mm

1 3102
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Ce
+ Dm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Dm
+ Rn
+ Hs

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Last updated: 15 Jul 2024