HitPredict

Interactor 1: A2RRC9 (A2RRC9)
IQ motif containing GTPase activating protein 3
Gene: IQGAP3

Interactor 2: B4DJ51 (B4DJ51)
Calmodulin 1 (Phosphorylase kinase, delta), isoform CRA_a (Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_b) (Epididymis secretory protein Li 72) (cDNA FLJ61744, highly similar to Calmodulin)
Gene: HEL-S-72

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~EF-hand_7, EF-hand_7~IQ
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1631 Hs			1 149
+	Hs
		483946 IQGA3_HUMAN (1-1631): 0: 1687: 99.82		CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		484020 IQGA3_HUMAN (1-1631): 0: 1687: 99.82		CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		484161 IQGA3_HUMAN (1-1631): 0: 1687: 99.82		CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		483913 IQGA1_HUMAN (6-1631): 0: 1551: 59.05		CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		483984 IQGA1_HUMAN (6-1631): 0: 1551: 59.05		CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		484079 IQGA1_HUMAN (6-1631): 0: 1551: 59.05		CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		648473 IQGA1_HUMAN (6-1631): 0: 1551: 59.05		CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56
+	Hs
		648499 IQGA2_HUMAN (86-1631): 0: 1333: 42.50		CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56
+	Hs
		484218 MYO5B_HUMAN (696-1522): 1.78e-100: 360: 13.71		CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Dm
		51918 A1Z6Z9_DROME (699-1532): 6.15e-99: 355: 12.64		CALL_DROME (3-149): 9.23e-57: 175: 66.67
+	Dm
		51921 A1Z6Z9_DROME (699-1532): 6.15e-99: 355: 12.64		CALM_DROME (1-149): 5.63e-56: 173: 97.99
+	Hs
		484206 MYO5C_HUMAN (699-1480): 8.19e-92: 332: 12.59		CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		483957 SYGP1_HUMAN (998-1345): 9.09e-66: 248: 16.34		CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Sc
		420355 IQG1_YEAST (31-265): 6.18e-27: 122: 25.11		CALM_YEAST (1-75): 2.74e-14: 67.4: 40.79
+	Sp
		144978 IQG1_SCHPO (657-1020): 4.31e-25: 116: 18.13		CALM_SCHPO (73-149): 6.82e-15: 69.1: 40.26