HitPredict

Interactor 1: DNLI1 (P18858)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: LIG1

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	34079125, 33097091
Identification Methods	proximity labelling technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 919 Hs			1 183
+	Hs
		579491 DNLI1_HUMAN (1-919): 0: 819: 100.00		CDYL_HUMAN (16-165): 6.53e-34: 127: 25.16
+	Hs
		579492 DNLI1_HUMAN (1-919): 0: 819: 100.00		CDY1_HUMAN (27-124): 4.91e-26: 105: 28.16
+	Hs
		579476 DNLI1_HUMAN (1-919): 0: 819: 100.00		CDYL2_HUMAN (28-125): 3.12e-25: 102: 28.43
+	Hs
		836721 DNLI3_HUMAN (149-905): 0: 570: 22.31		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		836782 DNLI3_HUMAN (149-905): 0: 570: 22.31		CBX8_HUMAN (21-116): 2.34e-26: 104: 32.00
+	Hs
		1027054 NIPBL_HUMAN (4-441): 2.08e-26: 119: 9.71		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800421 NIPBL_HUMAN (4-441): 2.08e-26: 119: 9.71		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949814 NIPBL_HUMAN (4-441): 2.08e-26: 119: 9.71		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33