HitPredict

Interactor 1: DNLI1 (P18858)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: LIG1

Interactor 2: UHRF1 (Q96T88)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.713

Property	Details
Experiments	28803780, 30639225, 32428527, 33097091, 36458887
Identification Methods	affinity chromatography technology, pull down, x-ray crystallography, unspecified method, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 919 Hs			1 793
+	Hs
		836762 DNLI3_HUMAN (149-905): 0: 570: 22.31		UHRF2_HUMAN (1-793): 0: 774: 53.01
+	Hs
		836718 DNLI3_HUMAN (149-905): 0: 570: 22.31		CHD3_HUMAN (101-502): 7.48e-52: 198: 13.90
+	Hs
		836727 DNLI3_HUMAN (149-905): 0: 570: 22.31		CHD4_HUMAN (233-502): 9.71e-49: 189: 15.00
+	Dm
		65197 Q9VG84_DROME (279-906): 6.32e-176: 531: 22.69		A8DYA3_DROME (299-468): 2.77e-09: 63.3: 19.78
+	Hs
		979879 IF4G1_HUMAN (16-457): 2.36e-34: 144: 14.76		CHD3_HUMAN (101-502): 7.48e-52: 198: 13.90
+	Hs
		979908 IF4G1_HUMAN (16-457): 2.36e-34: 144: 14.76		CHD4_HUMAN (233-502): 9.71e-49: 189: 15.00
+	Hs
		1059764 TITIN_HUMAN (40-379): 1.11e-09: 65.1: 9.87		CHD4_HUMAN (233-502): 9.71e-49: 189: 15.00