HitPredict

Interactor 1: XRCC1 (P18887)
DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)
Gene: XRCC1

Interactor 2: APEX1 (P27695)
DNA repair nuclease/redox regulator APEX1 (EC 3.1.11.2) (EC 3.1.21.-) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (APE-1) (DNA-(apurinic or apyrimidinic site) endonuclease) (Redox factor-1) (REF-1) [Cleaved into: DNA repair nuclease/redox regulator APEX1, mitochondrial]
Gene: APEX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.55 0.632

The method score is based on:

Property Details
Experiments 28986522, 11707423, 19934257
Identification Methods affinity chromatography technology, two hybrid, far western blotting, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006284 - base-excision repair
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024