Interactor 1: XRCC1 (P18887)
DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)
Gene: XRCC1
Interactor 2: APLF (Q8IW19)
Aprataxin and PNK-like factor (EC 3.1.-.-) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1)
Gene: APLF
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.55 | 0.719 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 27067600, 28514442, 33961781, 17353262, 17396150, 23178593 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation, far western blotting, fluorescence microscopy, two hybrid, anti tag coimmunoprecipitation, filter binding, pull down |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000012 - single strand break repair GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006303 - double-strand break repair via nonhomologous end joining GO:0072572 - poly-ADP-D-ribose binding and 2 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
