HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: SEH1 (P53011)
Nucleoporin SEH1 (Nuclear pore protein SEH1) (SEC13 homolog 1)
Gene: SEH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 349
+	Hs
		468239 HS90B_HUMAN (5-705): 0: 1016: 61.15		WDR5_HUMAN (103-349): 2.22e-58: 193: 16.53
+	Hs
		468668 HS90B_HUMAN (5-705): 0: 1016: 61.15		FBXW7_HUMAN (3-285): 1.27e-54: 191: 13.24
+	Hs
		461786 HS90A_HUMAN (4-705): 0: 1007: 60.67		FBXW7_HUMAN (3-285): 1.27e-54: 191: 13.24
+	Sc
		580036 HSC82_YEAST (1-705): 0: 971: 100.00		SEC13_YEAST (1-346): 8.63e-68: 216: 21.51
+	Sc
		393307 HSP82_YEAST (1-705): 0: 963: 95.63		SEC13_YEAST (1-346): 8.63e-68: 216: 21.51
+	Hs
		468157 HS90B_HUMAN (5-705): 0: 1016: 61.15		LIS1_HUMAN (201-349): 1.58e-33: 129: 14.09
+	Hs
		461248 HS90A_HUMAN (4-705): 0: 1007: 60.67		LIS1_HUMAN (201-349): 1.58e-33: 129: 14.09
+	Hs
		573420 ENPL_HUMAN (3-680): 0: 887: 47.10		WDR5_HUMAN (103-349): 2.22e-58: 193: 16.53
+	Hs
		573609 ENPL_HUMAN (3-680): 0: 887: 47.10		FBXW7_HUMAN (3-285): 1.27e-54: 191: 13.24
+	Sc
		580073 HSC82_YEAST (1-705): 0: 971: 100.00		CIAO1_YEAST (178-346): 5.16e-11: 64.9: 24.16
+	Hs
		573372 ENPL_HUMAN (3-680): 0: 887: 47.10		LIS1_HUMAN (201-349): 1.58e-33: 129: 14.09
+	Hs
		302740 ENPL_HUMAN (3-680): 0: 887: 47.10		CIAO1_HUMAN (7-145): 1e-17: 85: 19.87