Interactor 1: CDC42 (P19073)
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)
Gene: CDC42

Interactor 2: RGA1 (P39083)
Rho-type GTPase-activating protein 1
Gene: RGA1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 7498791, 11489916, 29074565, 18166650, 12455995, 11046150, 15020407
Identification Methods two hybrid, enzymatic study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RhoGAP
Common GO terms GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001403 - invasive growth in response to glucose limitation
GO:0005935 - cellular bud neck
GO:0007015 - actin filament organization
GO:0007118 - budding cell apical bud growth
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Sc

1 1007
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024