HitPredict

Interactor 1: CDC42 (P19073)
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)
Gene: CDC42

Interactor 2: RGD2 (P43556)
Rho-GTPase-activating protein RGD2
Gene: RGD2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	11591390
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005886 - plasma membrane GO:0005934 - cellular bud tip GO:0005935 - cellular bud neck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Sc			1 714
+	Hs
		564738 RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48		PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11
+	Hs
		925732 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11
+	Hs
		951457 RHOG_HUMAN (1-191): 1.71e-81: 241: 58.64		PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11
+	Hs
		564730 RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48		PACN3_HUMAN (4-403): 9.15e-87: 281: 14.29
+	Hs
		925717 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		PACN3_HUMAN (4-403): 9.15e-87: 281: 14.29
+	Hs
		894574 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		PACN3_HUMAN (4-403): 9.15e-87: 281: 14.29
+	Hs
		564542 RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48		CIP4_HUMAN (9-390): 1.31e-59: 213: 14.76
+	Hs
		564653 RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48		FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29
+	Hs
		894037 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		CIP4_HUMAN (9-390): 1.31e-59: 213: 14.76
+	Hs
		925540 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29
+	Hs
		951252 RHOG_HUMAN (1-191): 1.71e-81: 241: 58.64		FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29
+	Hs
		894338 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29
+	Hs
		925339 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		FBP1L_HUMAN (9-226): 1.55e-51: 190: 14.80
+	Hs
		894105 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		FBP1L_HUMAN (9-226): 1.55e-51: 190: 14.80
+	Hs
		564496 RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48		FCHO2_HUMAN (1-236): 3.53e-44: 172: 15.06
+	Hs
		925230 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		FCHO2_HUMAN (1-236): 3.53e-44: 172: 15.06
+	Hs
		950948 RHOG_HUMAN (1-191): 1.71e-81: 241: 58.64		FCHO2_HUMAN (1-236): 3.53e-44: 172: 15.06
+	Hs
		893940 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		FCHO2_HUMAN (1-236): 3.53e-44: 172: 15.06
+	Hs
		925414 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		NOSTN_HUMAN (17-247): 9.9e-34: 137: 13.19
+	Hs
		894191 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		NOSTN_HUMAN (17-247): 9.9e-34: 137: 13.19