HitPredict

Interactor 1: CDC42 (P19073)
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)
Gene: CDC42

Interactor 2: MSB4 (Q12317)
GTPase-activating protein MSB4 (Multicopy suppressor of bud emergence 4)
Gene: MSB4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	16166638
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0000131 - incipient cellular bud site GO:0005934 - cellular bud tip GO:0005935 - cellular bud neck GO:0030010 - establishment of cell polarity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Sc			1 492
+	Sc
		580326 CDC42_YEAST (1-191): 2.07e-79: 236: 100.00		GYP3_YEAST (24-483): 4.99e-99: 313: 47.40
+	Hs
		564635 RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48		US6NL_HUMAN (50-489): 5.41e-89: 291: 19.78
+	Hs
		564554 RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48		TB10B_HUMAN (21-471): 6.81e-89: 290: 19.44
+	Hs
		925494 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		US6NL_HUMAN (50-489): 5.41e-89: 291: 19.78
+	Hs
		925323 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		TB10B_HUMAN (21-471): 6.81e-89: 290: 19.44
+	Hs
		951204 RHOG_HUMAN (1-191): 1.71e-81: 241: 58.64		US6NL_HUMAN (50-489): 5.41e-89: 291: 19.78
+	Hs
		894279 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		US6NL_HUMAN (50-489): 5.41e-89: 291: 19.78
+	Hs
		1270182 RHOJ_HUMAN (2-189): 4.76e-79: 236: 59.04		US6NL_HUMAN (50-489): 5.41e-89: 291: 19.78
+	Hs
		545541 RAC2_HUMAN (1-191): 1.83e-79: 236: 67.71		US6NL_HUMAN (50-489): 5.41e-89: 291: 19.78
+	Hs
		1117432 RHOJ_HUMAN (2-189): 4.76e-79: 236: 59.04		TB10B_HUMAN (21-471): 6.81e-89: 290: 19.44
+	Hs
		900761 RHOA_HUMAN (5-191): 9.78e-79: 234: 51.34		US6NL_HUMAN (50-489): 5.41e-89: 291: 19.78
+	Hs
		321279 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		TBCD8_HUMAN (38-476): 1.37e-78: 267: 21.97
+	Hs
		321304 RHOJ_HUMAN (2-189): 4.76e-79: 236: 59.04		TBCD8_HUMAN (38-476): 1.37e-78: 267: 21.97
+	Hs
		232655 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		TBCD4_HUMAN (3-491): 1.92e-75: 260: 18.42
+	Hs
		715076 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		UBP6_HUMAN (41-436): 1.16e-72: 252: 20.83
+	Hs
		894392 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		TBD2A_HUMAN (43-455): 1.25e-75: 257: 25.72
+	Hs
		715074 CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11		UBP6_HUMAN (41-436): 1.16e-72: 252: 20.83
+	Ce
		975574 RAC1_CAEEL (1-191): 3.61e-84: 248: 66.49		Q23419_CAEEL (94-391): 9.3e-28: 119: 28.90
+	Hs
		925738 RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75		TBD2B_HUMAN (113-402): 1.77e-24: 109: 31.19
+	Hs
		951462 RHOG_HUMAN (1-191): 1.71e-81: 241: 58.64		TBD2B_HUMAN (113-402): 1.77e-24: 109: 31.19