HitPredict

Interactor 1: GNAZ (P19086)
Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha)
Gene: GNAZ

Interactor 2: DRD5 (P21918)
D(1B) dopamine receptor (D(5) dopamine receptor) (D1beta dopamine receptor) (Dopamine D5 receptor)
Gene: DRD5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9603210
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	7tm_1~G-alpha
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 477
+	Hs
		602211 GNAS2_HUMAN (1-354): 2.36e-167: 473: 37.22		DRD5_HUMAN (1-477): 7.74e-130: 386: 100.00
+	Hs
		602214 GNA13_HUMAN (2-354): 1.24e-156: 446: 39.17		DRD5_HUMAN (1-477): 7.74e-130: 386: 100.00
+	Hs
		391305 GNAI2_HUMAN (1-354): 2.1e-177: 497: 66.38		ADRB2_HUMAN (1-419): 4.5e-82: 261: 28.84
+	Hs
		429011 GNAI1_HUMAN (1-354): 9.58e-177: 495: 67.23		ADRB2_HUMAN (1-419): 4.5e-82: 261: 28.84
+	Hs
		428884 GNAI3_HUMAN (1-354): 5.24e-174: 489: 67.23		ADRB2_HUMAN (1-419): 4.5e-82: 261: 28.84
+	Hs
		429010 GNAS2_HUMAN (1-354): 2.36e-167: 473: 37.22		ADRB2_HUMAN (1-419): 4.5e-82: 261: 28.84
+	Hs
		428911 GNAT2_HUMAN (1-354): 3.65e-167: 471: 57.06		ADRB2_HUMAN (1-419): 4.5e-82: 261: 28.84
+	Hs
		450980 GNAO_HUMAN (1-354): 2.98e-175: 492: 60.45		DRD3_HUMAN (25-375): 1.63e-34: 135: 30.00
+	Hs
		391310 GNAI2_HUMAN (1-354): 2.1e-177: 497: 66.38		ADA2A_HUMAN (255-373): 1.44e-11: 68.2: 34.88
+	Hs
		445801 GNAO_HUMAN (1-354): 2.98e-175: 492: 60.45		ADA2A_HUMAN (255-373): 1.44e-11: 68.2: 34.88