HitPredict

Interactor 1: GNAZ (P19086)
Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha)
Gene: GNAZ

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31501420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 504
+	Hs
		391445 GNAI2_HUMAN (1-354): 2.1e-177: 497: 66.38		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		125350 GNAS2_HUMAN (1-354): 2.36e-167: 473: 37.22		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		391350 GNAI2_HUMAN (1-354): 2.1e-177: 497: 66.38		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808488 GNAI1_HUMAN (1-354): 9.58e-177: 495: 67.23		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		450987 GNAO_HUMAN (1-354): 2.98e-175: 492: 60.45		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		444684 GNAI3_HUMAN (1-354): 5.24e-174: 489: 67.23		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808487 GNAS2_HUMAN (1-354): 2.36e-167: 473: 37.22		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		670431 GNA11_HUMAN (1-354): 4.25e-164: 464: 46.76		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		325960 GNA14_HUMAN (3-354): 5.71e-162: 458: 48.16		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808606 GNA13_HUMAN (2-354): 1.24e-156: 446: 39.17		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00