HitPredict

Interactor 1: GNAZ (P19086)
Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha)
Gene: GNAZ

Interactor 2: DCA10 (Q5QP82)
DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32)
Gene: DCAF10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	G-alpha~WD40
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 559
+	Hs
		391374 GNAI2_HUMAN (1-354): 2.1e-177: 497: 66.38		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		921512 GNAI1_HUMAN (1-354): 9.58e-177: 495: 67.23		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		444706 GNAI3_HUMAN (1-354): 5.24e-174: 489: 67.23		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		391370 GNAI2_HUMAN (1-354): 2.1e-177: 497: 66.38		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Ce
		567431 GNAO_CAEEL (1-354): 7.42e-171: 481: 59.89		GBB1_CAEEL (204-555): 4.44e-26: 111: 14.12
+	Hs
		444702 GNAI3_HUMAN (1-354): 5.24e-174: 489: 67.23		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		921511 GNAS2_HUMAN (1-354): 2.36e-167: 473: 37.22		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		921564 GNA13_HUMAN (2-354): 1.24e-156: 446: 39.17		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64