HitPredict

Interactor 1: ML12A (P19105)
Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)
Gene: MYL12A

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 171 Hs			1 721
+	Hs
		580653 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		484226 CALM3_HUMAN (16-92): 3.58e-09: 54.5: 24.69		LRRF2_HUMAN (1-721): 7.69e-104: 335: 100.00
+	Hs
		580656 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		MRCKA_HUMAN (231-721): 3.54e-31: 133: 11.66
+	Hs
		580616 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		MYH11_HUMAN (421-721): 1.67e-13: 76.8: 16.56
+	Hs
		159551 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MYH11_HUMAN (421-721): 1.67e-13: 76.8: 16.56
+	Hs
		580672 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		159604 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		580615 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Hs
		159550 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Mm
		1143166 Q6ZWQ9_MOUSE (1-171): 4.56e-64: 196: 97.09		MYH10_MOUSE (421-721): 3.37e-11: 69.1: 16.23
+	Hs
		159635 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MYH15_HUMAN (269-696): 2.05e-10: 66.5: 11.74
+	Hs
		624342 MYL9_HUMAN (14-171): 2.29e-64: 196: 94.30		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Hs
		580614 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		159549 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Dm
		773034 SQH_DROME (1-171): 2.38e-60: 186: 80.46		MYSN_DROME (310-715): 1.23e-12: 73.9: 12.62
+	Hs
		501101 MLRV_HUMAN (9-165): 2.99e-55: 173: 58.23		MYH1_HUMAN (218-720): 1.32e-16: 86.8: 9.27
+	Hs
		624341 MYL9_HUMAN (14-171): 2.29e-64: 196: 94.30		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		484173 CALM3_HUMAN (16-92): 3.58e-09: 54.5: 24.69		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		648467 CALL3_HUMAN (31-92): 1.25e-10: 58.2: 27.27		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12