HitPredict

Interactor 1: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	15265939, 12115600, 18490752
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~I-set, Ank_2~I-set
Common GO terms	GO:0006954 - inflammatory response GO:0071356 - cellular response to tumor necrosis factor
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 968
+	Hs
		581688 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		TF65_HUMAN (28-420): 6.77e-116: 368: 34.41
+	Hs
		581886 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		KDIS_HUMAN (727-937): 1.36e-20: 100: 8.00
+	Hs
		581785 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		ANKH1_HUMAN (797-964): 4.27e-16: 85.7: 12.64
+	Hs
		257561 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		ANR17_HUMAN (854-961): 2.29e-09: 63.8: 12.04
+	Hs
		685308 L1CAM_HUMAN (4-739): 1.03e-29: 128: 11.41		ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37
+	Hs
		556716 TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24		ANK1_HUMAN (539-967): 7.32e-78: 281: 16.84
+	Hs
		166985 TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24		ANR28_HUMAN (650-967): 1.41e-49: 192: 14.82