HitPredict

Interactor 1: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Interactor 2: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005886 - plasma membrane GO:0032496 - response to lipopolysaccharide
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 256
+	Hs
		581478 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13
+	Hs
		581692 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54
+	Hs
		581464 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25