HitPredict

Interactor 1: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Interactor 2: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 639
+	Hs
		409001 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33
+	Hs
		380555 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94
+	Hs
		359464 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22
+	Hs
		409180 TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24		K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33
+	Hs
		234500 DSCAM_HUMAN (10-207): 2.99e-15: 82.3: 12.87		KRT83_HUMAN (83-491): 2.11e-86: 280: 49.02