HitPredict

Interactor 1: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 411
+	Hs
		581590 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75
+	Hs
		571301 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63
+	Hs
		581815 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79
+	Hs
		133875 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		581443 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83