HitPredict

Interactor 1: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~I-set
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 394
+	Hs
		581589 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		581659 VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00		ACTC_HUMAN (2-388): 0: 569: 46.51
+	Dm
		52376 A1Z7J1_DROME (35-621): 5.09e-63: 231: 17.83		ACT3_DROME (1-388): 0: 571: 45.36
+	Dm
		54871 A1ZA72_DROME (530-735): 3.74e-14: 78.9: 17.11		ACT6_DROME (1-388): 0: 571: 46.13