HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: SRC8 (Q66HL2)
Src substrate cortactin
Gene: Cttn

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 752 Rn			1 509
+	Rn
		94238 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		SRC8_RAT (1-509): 3.78e-175: 504: 100.00
+	Hs
		497012 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		SRC8_HUMAN (1-509): 4.48e-168: 487: 84.36
+	Hs
		1052365 CABIN_HUMAN (103-561): 3.85e-12: 72.2: 12.26		SRC8_HUMAN (1-509): 4.48e-168: 487: 84.36
+	Rn
		555250 TAU_RAT (1-752): 2.4e-95: 314: 100.00		SPTN1_RAT (104-508): 6.87e-47: 177: 15.01
+	Rn
		94140 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		SPTN1_RAT (104-508): 6.87e-47: 177: 15.01
+	Hs
		496988 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		SPTN1_HUMAN (104-508): 1.1e-47: 180: 15.50
+	Mm
		498047 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		PACN1_MOUSE (165-508): 2.04e-35: 139: 15.86
+	Hs
		497550 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		PACN1_HUMAN (165-508): 1.48e-34: 137: 15.01
+	Hs
		497761 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		DBNL_HUMAN (324-509): 1.39e-33: 133: 32.65
+	Hs
		497684 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		ABI2_HUMAN (284-506): 2.12e-29: 123: 18.88
+	Hs
		497507 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		SH3G2_HUMAN (322-508): 4.19e-29: 119: 22.34
+	Hs
		497030 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		LASP1_HUMAN (303-508): 3.19e-29: 117: 22.62
+	Hs
		497381 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		STAM1_HUMAN (380-505): 1.2e-12: 72.2: 23.02
+	Hs
		965102 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		SPTN1_HUMAN (104-508): 1.1e-47: 180: 15.50
+	Mm
		561172 ANK2_MOUSE (184-606): 1.18e-23: 109: 16.21		SPTN1_MOUSE (104-508): 4.9e-47: 178: 15.01
+	Hs
		1349277 DAPLE_HUMAN (3-620): 7.14e-32: 135: 10.16		ITSN2_HUMAN (348-507): 4.48e-19: 93.1: 18.13
+	Rn
		193638 SYNJ1_RAT (328-740): 1.95e-12: 73.2: 12.80		SH3G1_RAT (290-508): 7.37e-31: 125: 15.91
+	Rn
		192354 SYNJ1_RAT (328-740): 1.95e-12: 73.2: 12.80		SH3G2_RAT (322-508): 4.51e-31: 124: 22.87
+	Mm
		88459 D3Z656_MOUSE (377-751): 1.31e-09: 63.9: 12.53		SH3G2_MOUSE (322-508): 6.14e-29: 119: 21.28
+	Hs
		203191 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		VINEX_HUMAN (364-508): 1.43e-13: 75.4: 20.81