HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: PUF60 (Q9WV25)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (RNA-binding protein Siah-BP) (Siah-binding protein 1)
Gene: PUF60

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 564
+	Hs
		497752 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		PUF60_HUMAN (1-564): 1.71e-100: 316: 97.87
+	Hs
		497019 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		RBM39_HUMAN (118-560): 3.03e-70: 237: 19.33
+	Rn
		582032 TAU_RAT (1-752): 2.4e-95: 314: 100.00		PABP1_RAT (462-555): 1.09e-09: 63: 10.64
+	Rn
		94258 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		PABP1_RAT (462-555): 1.09e-09: 63: 10.64
+	Mm
		498050 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		ELAV4_MOUSE (27-215): 5.73e-20: 94.2: 18.56
+	Hs
		1054314 MDC1_HUMAN (4-740): 1.03e-26: 119: 9.08		RBM39_HUMAN (118-560): 3.03e-70: 237: 19.33
+	Mm
		498054 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		Q62029_MOUSE (454-563): 1.51e-13: 75.4: 13.64
+	Hs
		496346 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		ELAV4_HUMAN (27-215): 5.37e-20: 94.2: 18.56
+	Hs
		496957 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		PABP4_HUMAN (454-564): 8.13e-15: 79.6: 15.32
+	Hs
		311335 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		CELF2_HUMAN (214-384): 6.66e-13: 73.1: 10.23
+	Hs
		496179 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		PABP1_HUMAN (462-555): 1.09e-09: 63: 10.64
+	Hs
		965152 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		PABP3_HUMAN (454-564): 1.25e-14: 78.8: 15.32