HitPredict - High confidence protein-protein interactions

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	25313645, 21575138
Identification Methods	affinity chromatography technology, blue native page, surface plasmon resonance
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0001525 - angiogenesis GO:0001533 - cornified envelope GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 23 others more... GO:0005681 - spliceosomal complex GO:0005694 - chromosome GO:0005730 - nucleolus GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0016020 - membrane GO:0017148 - negative regulation of translation GO:0036464 - cytoplasmic ribonucleoprotein granule GO:0042162 - telomeric DNA binding GO:0042731 - PH domain binding GO:0043560 - insulin receptor substrate binding GO:0044547 - DNA topoisomerase binding GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046627 - negative regulation of insulin receptor signaling pathway GO:0048026 - positive regulation of mRNA splicing, via spliceosome GO:0048027 - mRNA 5'-UTR binding GO:0050730 - regulation of peptidyl-tyrosine phosphorylation GO:0070062 - extracellular exosome GO:0071364 - cellular response to epidermal growth factor stimulus GO:0160056 - macropinosome membrane GO:1901838 - positive regulation of transcription of nucleolar large rRNA by RNA polymerase I GO:1990830 - cellular response to leukemia inhibitory factor GO:1990904 - ribonucleoprotein complex
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1	710
Hs

1	710

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Last updated: 15 Jul 2024