HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27049334
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:1990830 - cellular response to leukemia inhibitory factor
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 164
+	Hs
		582249 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		516355 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		992875 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		267046 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54
+	Sc
		376562 PABP_YEAST (181-555): 3.61e-53: 194: 17.47		PABP_YEAST (2-93): 6.85e-19: 84.2: 20.62
+	Hs
		1119141 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PAP1L_HUMAN (1-94): 4.25e-21: 90.7: 22.55
+	Hs
		516635 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		516466 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		516478 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		1028593 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	Hs
		266904 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		516425 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		516495 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	Hs
		516339 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		516689 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP3_HUMAN (1-91): 6.48e-19: 84.6: 23.71
+	Hs
		516493 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	Mm
		665745 PABP1_MOUSE (222-482): 5.43e-43: 167: 15.55		TIA1_MOUSE (5-107): 1.59e-18: 82.6: 21.70
+	Hs
		516674 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		RBM4_HUMAN (11-88): 3.45e-18: 81.9: 28.21
+	Hs
		516471 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		TIAR_HUMAN (1-95): 5.6e-18: 81.1: 26.00